The image above is of the 200 block of East Georgia Street (in Chinatown), made in the 1960s. If you compare this image with the one immediately below, there are really very few substantive changes to the buildings on the block, so far. That will change, soon, with the re-development of the second building in from the western end of this block (the storefront/residence with the peaked roof tucked between the two apparent tenement blocks, as shown above) and today ( below, where the development is happening at the left side of the image).
One of the common businesses in both images is Ho Sun Hing Printers, which was at that location from 1908 until March, 2014. For more about this historic print shop, see this John Mackie feature for the Vancouver Sun and this video also produced for the Sun.
(Note: It looks as though there is another common business type between these images from the 1960s and 2015 is in the orange building adjacent to Ho Sun Hing. Although there seems not to be a visible English sign on the structure in the 1960s image, the truck in front of the building advertises “Centennial Hatcheries and Breeding Farms”. Today, the orange building has on its English sign “Fresh Egg Market”. )